One single reading of S pO 2 by pulse oximeter and its corresponding simultaneous S aO 2 were obtained per subject. After 1 min of a stable S pO 2 reading, a simultaneous ABG reading was obtained from the radial artery for ABG analysis. A single pulse oximeter was used for all subjects. Pulse oximetry was used to measure S pO 2 in these COPD candidates using a Nellcor N-200 (Nellcor, Hayward, California) co-oximeter finger probe in a sitting position. 5 Subjects with dyspnea, chronic cough, and/or sputum production and a history of exposure to risk factors and a post-bronchodilator FEV 1/FVC of 35 breaths/min and/or active contraction of the accessory muscles of respiration or paradoxical abdominal motion (2) hypercapnia (P aCO 2 > 50 mm Hg) with respiratory acidosis (pH <7.33) and (3) hypoxemia (S aO 2 < 90%). The diagnosis of COPD was considered following the Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2013 guidelines. Patients with icterus, other respiratory disorders, and other systemic disorders compromising or altering respiratory function were excluded. We performed a prospective observational study to assess the performance of handheld pulse oximetry in predicting hypoxemia in subjects with an exacerbation of COPD and to compare the efficacy of handheld pulse oximetry in the diagnosis of hypoxemia in chronic bronchitis and emphysema.įifty consecutive subjects diagnosed with COPD with acute respiratory failure attending the Department of General Medicine, Government General Hospital, a 1,000-bed tertiary hospital in Guntur, India, over a period of 1 month were enrolled into the study. 4 However, the data were gathered from studies in subjects with shock and ARDS. Studies on the performance of pulse oximetry show that: (1) there is a very strong correlation (r = 0.91) of S aO 2 readings with S pO 2 values 1 but only moderate correlation between the degree of change (2) the pulse oximeter overestimates actual changes in S aO 2 2, 3 and (3) high S pO 2 thresholds are necessary to detect significant hypoxemia with pulse oximetry. Pulse oximetry has become a standard practice in monitoring oxygen levels in the patient's blood. Noninvasive measurement of arterial S pO 2 is obtained by an instrument called a pulse oximeter. Obtaining accurate data regarding the oxygenation saturation of hemoglobin in blood (S aO 2) requires invasive arterial blood gas (ABG) analysis. These episodes of acute respiratory failure can be diagnosed by measuring the oxygen saturation of hemoglobin in the blood. COPD is a relentlessly progressive debilitating disease, punctuated by exacerbations of acute respiratory failure.
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